A ketamine overdose can be fatal within minutes if breathing becomes severely depressed or stops completely. Recognising the five critical warning signs – breathing problems, unconsciousness, extreme confusion, severe vomiting, and hallucinations – could mean the difference between life and death for someone you care about.
Yes, ketamine overdose can be fatal, particularly when the drug depresses breathing to dangerous levels or causes complete respiratory failure. Death rates increase dramatically when ketamine is mixed with alcohol, opioids, or other depressant drugs, which compound the life-threatening effects.
The drug’s unpredictable potency on the street makes overdose risk even higher, as users cannot know the actual strength or purity of what they’re taking.
These five symptoms indicate a medical emergency requiring immediate 999 calls, as they can rapidly become life-threatening without professional intervention.
Call 999 immediately – don’t wait to see if symptoms improve, as ketamine overdose can worsen rapidly. Time is critical when breathing is compromised, and paramedics carry life-saving equipment you don’t have at home.
Emergency steps to take:
|
Action |
Why It’s Critical |
|
Call 999 first |
Breathing can stop within minutes |
|
Check breathing |
Count breaths – under 10 per minute is dangerous |
|
Recovery position |
Prevents choking if they vomit |
|
Stay with them |
Monitor breathing until help arrives |
|
Give rescue breathing |
If trained and they’ve stopped breathing |
Never leave someone alone during a suspected overdose – their condition can deteriorate from stable to fatal in minutes.
Yes, combining ketamine with alcohol, opioids, benzodiazepines, or other depressants multiplies overdose risk exponentially. These combinations can cause respiratory depression, heart failure, and death even at doses that might normally be survivable.
Particularly dangerous combinations:
• Ketamine + alcohol (extremely common and deadly)
• Ketamine + heroin or other opioids
• Ketamine + benzodiazepines (Xanax, Valium) • Ketamine + GHB or other club drugs
The unpredictable street purity of ketamine makes any combination potentially lethal, as users cannot accurately judge dosing.
Regular ketamine use that continues despite negative consequences indicates addiction requiring professional treatment. Early intervention prevents escalation to life-threatening overdose situations.
Clear addiction warning signs:
• Using ketamine daily or multiple times per week
• Unable to enjoy activities without ketamine
• Continuing use despite health, relationship, or legal problems
• Experiencing withdrawal symptoms when trying to stop
• Lying about or hiding ketamine use from loved ones
Help4Addiction provides 24/7 crisis support and connects you with emergency ketamine treatment services across the UK. Whether you need immediate overdose support, addiction treatment, or are worried about someone’s ketamine use, we can direct you to appropriate help.
Our experienced team understands ketamine addiction and overdose risks. We work with leading treatment centres, NHS services, and private facilities to ensure you receive the right level of care for your situation – from emergency medical support to comprehensive addiction treatment programmes.
Nicholas Conn is a leading industry addiction expert who runs the UK’s largest addiction advisory service and is regularly featured in the national press, radio and TV. He is the founder and CEO of a drug and alcohol rehab center called Help4addiction, which was founded in 2015. He has been clean himself since 2009 and has worked in the Addiction and Rehab Industry for over a decade. Nick is dedicated to helping others recover and get treatment for drug and alcohol abuse. In 2013, he released a book ‘The Thin White’ line that is available on Amazon.
Who am I contacting?
Calls and contact requests are answered by our admissions team at Help 4 Addiction. We work with a network of addiction rehabs throughout the UK and also some internationally. We do not own any of these clinics and we receive payment for our referral services.
We look forward to helping you take your first step.